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Neurology
The state-of-the-art of neurology at your fingertips: Our physician editors identify experts to comment on the most compelling original research and review articles in their fields.
Featured Article
SUMMARY AND COMMENT
Preventative Treatment of Intracranial Aneurysms
- November 3, 2009
- Rose Du, MD, PhD
A new cost-effectiveness analysis addresses some clinically important questions.
- Reviewing:
- Greving JP et al. Neurology 2009 Jul 28; 73:258
Recent Neurology Articles
SUMMARY AND COMMENT
Genetic Causes of Dopa-Responsive Dystonia
- November 3, 2009
- Nutan Sharma, MD, PhD
Parkinsonism is not the only clinical syndrome associated with abnormal dopamine levels.
- Reviewing:
- Clot F et al. Brain 2009 Jul; 132:1753
SUMMARY AND COMMENT
Quality of Life with Psychogenic Nonepileptic Seizures
- November 3, 2009
- Gregory Fricchione, MD
Psychiatric symptoms affect quality of life more than seizure frequency does.
- Reviewing:
- LaFrance WC Jr and Syc S. Neurology 2009 Aug 4; 73:366
SUMMARY AND COMMENT
Subjectively Poor Sleep Correlates with Postpartum Depression
- November 3, 2009
- Brian J. Murray MD, FRCPC D, ABSM
In a questionnaire study, this association held true even after adjustments for other known risk factors for depression.
- Reviewing:
- Dørheim SK et al. Sleep 2009 Jul; 32:847
SUMMARY AND COMMENT
VECTORS Study: Are We Going in the Right Direction?
- October 27, 2009
- Joel Stein, MD
Contrary to expectation, high-intensity constraint-induced therapy produced worse outcomes than lower-intensity constraint-induced therapy or conventional therapy when used early after stroke.
- Reviewing:
- Dromerick AW et al. Neurology 2009 Jul 21; 73:195
SUMMARY AND COMMENT
Psychological Health in Central Hypersomnias: The French Harmony Study
- October 27, 2009
- Demetrios A. Julius, MD
An ambitious and impressive study of central hypersomnias — including cataplectic narcolepsy, narcolepsy without cataplexy, and idiopathic hypersomnia — helps to clarify the associations of these entities with each other, with depressive symptomatology, and with treatment response.
- Reviewing:
- Dauvilliers Y et al. J Neurol Neurosurg Psychiatry 2009 Jun; 80:636
SUMMARY AND COMMENT
Does Hypothermia Lead to Better Outcomes in Newborns with Asphyxial Encephalopathy?Free
- October 7, 2009
- William P. Kanto, Jr., MD
- Pediatrics and Adolescent Medicine
Hypothermia did not lower mortality but did lead to better neurological outcomes in survivors.
- Reviewing:
- Azzopardi DV et al. N Engl J Med 2009 Oct 1; 361:1349
SUMMARY AND COMMENT
FOUR Score Coma Scale in Medical Intensive CareFree
- October 20, 2009
- David M. Greer, MD, MA
This relatively new coma assessment scale performed well in predicting outcome in medical intensive care, but it needs further validation.
- Reviewing:
- Iyer VN et al. Mayo Clin Proc 2009 Aug; 84:694
SUMMARY AND COMMENT
Neurological Comorbidity and Epilepsy Treatment
- October 20, 2009
- Andrew J. Cole, MD, FRCP(C)
A review highlights the dearth of class 1 evidence regarding optimal epilepsy treatment and drug–drug interactions in the setting of comorbid disease.
- Reviewing:
- Zaccara G. Acta Neurol Scand 2009 Jul; 120:1
SUMMARY AND COMMENT
Link Found Between Sleep Loss and Colitis
- October 20, 2009
- Jeffrey M. Ellenbogen, MMSc, MD
In mice, sleep deprivation worsens colonic inflammation.
- Reviewing:
- Tang Y et al. Sleep Med 2009 Jun; 10:597
SUMMARY AND COMMENT
Neuroimaging with Pittsburgh Compound B in Patients with Mild Cognitive Impairment
- October 13, 2009
- Rawan Tarawneh, MD, and John C. Morris, MD
MCI patients with amyloid retention identified by PiB most likely have very early AD.
- Reviewing:
- Wolk DA et al. Ann Neurol 2009 May; 65:557
Journal Watch Neurology summarizes important medical journal articles about a wide variety of neurologic subjects including Alzheimer disease, autoimmune disease, epilepsy, headache, movement disorders, multiple sclerosis, neuropathy, Parkinson disease, sleep, and stroke.
