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Parkinson's Disease
Physician-authored summaries on the latest research on Parkinson's disease, editorials on Parkinson's disease, and perspectives on Parkinson's disease - drawn from the top medical journals.
You searched for: Parkinson's disease Items 1 to 20 of 117 results
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Are Antihypertensive Drugs Neuroprotective in Parkinson Disease?
- April 15, 2008
- Robert L. Rodnitzky, MD
A large case-control study suggests that calcium channel blockers are the only antihypertensives that reduce the risk for Parkinson disease.- Covering:
- Becker C et al., Neurology 2008 Feb 6;:
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Distraction Increases Driving Errors in People With and Those Without Parkinson Disease
- April 17, 2007
- Germaine L. Odenheimer, MD
During an on-road driving test, patients with Parkinson disease performed worse than controls, but adding a distraction caused a similar degree of worsened performance in both groups.- Covering:
- Uc EY et al., Neurology 2006 Nov 28; 67:1774-80.
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Sleep Disorder Associated with Hallucinations in Parkinson DiseaseFree!
- October 10, 2006
- Christopher I. Wright, MD, PhD
In this study with moderate clinical relevance, hallucinations in Parkinson disease were associated with REM sleep behavior disorder.- Covering:
- Benbir G et al., Acta Neurol Scand 2006 Oct; 114:239-43.
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Psychosocial Effects of Deep Brain Stimulation? Or the Perils of Getting Better?
- October 3, 2006
- Alice Flaherty, MD, PhD
Two articles present new findings on psychiatric, social, and cognitive impairments associated with deep brain stimulation for Parkinson disease.- Covering:
- Schüpbach M et al., Neurology 2006 Jun 27; 66:1811-6.
- Smeding HM et al., Neurology 2006 Jun 27; 66:1830-6.
- Saint-Cyr JA and Albanese A., Neurology 2006 Jun 27; 66:1799-800.
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Deep Brain Stimulation for Advanced Parkinson Disease: Long-Term Follow-Up
- February 23, 2006
- Wendy R. Galpern, MD, PhD
Studies have demonstrated the short-term efficacy of deep brain stimulation (DBS) for advanced Parkinson disease (PD), yet we have limited long-term follow-up data. In this . . .- Covering:
- Rodriguez-Oroz MC et al., Brain 2005 Oct; 128:2240-9.
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Is Pergolide Use Associated with Valvular Heart Disease?
- January 12, 2006
- Michael S. Okun, MD
Waller and colleagues examined the frequency of valvular heart disease in patients taking pergolide (an ergot-derived dopamine agonist) for restless legs syndrome, Parkinson disease, or . . .- Covering:
- Waller EA et al., Mayo Clin Proc 2005 Aug; 80:1016-20.
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Camptocormia: A Heterogeneous Disorder
- December 29, 2005
- H. Royden Jones, Jr., MD
Camptocormia, a condition marked by abnormal bending of the trunk, is an unusual, often misdiagnosed disorder. Parkinson disease (PD) frequently precedes camptocormia, but it sometimes . . .- Covering:
- Azher SN and Jankovic J., Neurology 2005 Aug 9; 65:355-9.
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The Value of β-CIT SPECT for Diagnosing PD
- November 3, 2005
- Lewis Sudarsky, MD
No lab test or biomarker is known to support a diagnosis of Parkinson disease (PD). A variety of diagnostic imaging techniques have been developed using . . .- Covering:
- Eerola J et al., J Neurol Neurosurg Psychiatry 2005 Sep; 76:1211-6.
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Does Levodopa Affect Parkinson Disease Progression?
- March 11, 2005
- Anthony H. V. Schapira, MD, DSc, FRCP, FMedSci
Levodopa is very effective in ameliorating the motor symptoms related to nigral dopaminergic cell death in patients with Parkinson disease (PD). However, there are concerns . . .- Covering:
- Fahn S et al. for the Parkinson Study Group., N Engl J Med 2004 Dec 9; 351:2498-508.
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Potential Biomarkers for Parkinson Disease
- November 5, 2004
- David Standaert, MD, PhD
Parkinson disease (PD) is currently diagnosed and monitored by clinical examination, but this approach is far from foolproof. Even in specialized centers, up to 10% . . .- Covering:
- Michell AW et al., Brain 2004 Aug; 127:1693-705.
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Update on Genetic Involvement in Parkinson Disease
- June 11, 2004
- Matthew S. Goldberg, PhD
For years, the etiology of Parkinson disease (PD) was believed to be strictly nongenetic. This review of research on the genes synuclein and parkin highlights . . .- Covering:
- Burke RE., Neurologist 2004 Mar; 10:75-81.
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More on Psychosis in Parkinson Disease
- September 25, 2003
- Gary Tucker, MD
Two recent studies delineate intriguing aspects of psychosis in Parkinson disease (PD).- Covering:
- Factor SA et al., Neurology 2003 Jun 10; 60:1756-61.
- Kaiser R et al., Neurology 2003 Jun 10; 60:1750-5.
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Pallidotomy Better Than Medical Management for Advanced Parkinson Disease
- July 24, 2003
- Lewis Sudarsky, MD
To compare pallidotomy with best medical therapy in patients with Parkinson disease (PD), researchers randomized 36 patients (mean age, 58.5) who met their medical center's . . .- Covering:
- Vitek JL et al., Ann Neurol 2003 May; 53:558-69.
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Implications of Genetic Advances in Alzheimer's and Parkinson Disease
- July 11, 2003
- Stefan M. Pulst, MD
Nussbaum and Ellis review advances in understanding the genetic aspects of Alzheimer's disease (AD) and Parkinson disease (PD), two seemingly disparate diseases that share complex . . .- Covering:
- Nussbaum RL and Ellis CE., N Engl J Med 2003 Apr 3; 348:1356-64.
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Chromosome 1p Holds Clues to Pathogenetic Pathway of Parkinson Disease
- January 10, 2003
- Michael Schlossmacher, MD
Two recent reports highlight the relevance of genetic contributions to the etiology of Parkinson disease (PD).- Covering:
- Bonifati V et al., SciencExpress 2002 Nov 21;:
- Hicks AA et al., Ann Neurol 2002 Nov; 52:549-55.
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The State of Drug Trials for Parkinson's Disease Treatments
- October 24, 2002
- Christopher G. Goetz, MD
These authors reviewed the literature on drug treatments for Parkinson's disease (PD), focusing on the quality of study design and execution. Their critique is harsh: . . .- Covering:
- Wheatley K et al., BMJ 2002 Jun 22; 324:1508-11.
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Evidence-Based Assessment of Treatments for Parkinson's Disease
- July 25, 2002
- Anthony E. Lang, MD
This rigorous, evidence-based review of available treatments for Parkinson's disease should aid specialists and nonspecialists alike.- Covering:
- Rascol O et al., Lancet 2002 May 4; 359:1589-98.
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New Evidence for Genetic Contribution to Parkinson's Disease
- May 10, 2002
- Joseph H. Friedman, MD
Although some degree of familial aggregation of Parkinson's disease (PD) has been recognized for more than a century, the disease was until recently considered a . . .- Covering:
- Nicholl DJ et al., Brain 2002 Jan; 125:44-57.
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Welding May Be an Environmental Trigger for Parkinson's Disease
- April 12, 2001
- KD Sethi
These authors sought to determine whether welding-related parkinsonism is clinically different from idiopathic Parkinson's disease (PD). Their case-control study compared 15 career welders who had . . .- Covering:
- Racette BA et al., Neurology 2001 Jan 9; 56:
8 13 .
- Racette BA et al., Neurology 2001 Jan 9; 56:
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Genetic Factors in Parkinson's Disease in Iceland
- February 21, 2001
- CM Tanner
Evidence supporting a genetic cause of Parkinson's disease (PD) is most robust in the less than 5 percent of cases with onset before age 50. . . .- Covering:
- Sveinbjornsdottir S et al., N Engl J Med 2000 Dec 14; 343:
1765 1770 .
- Sveinbjornsdottir S et al., N Engl J Med 2000 Dec 14; 343:
You searched for: Parkinson's disease Items 1 to 20 of 117 results