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You searched for: aphasia in Neurology
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Pathology in Primary Progressive Aphasia
- September 30, 2008
- Andrew Kertesz, MD, FRCP(C)
- Neurology
Clinical subtypes of PPA do not correlate one-to-one with pathology.- Reviewing:
- Mesulam M et al., Ann Neurol 2008 Jun; 63:709.
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Aphasia and Apraxia of Speech: Clinical, Imaging, and Pathologic Correlates
- July 6, 2006
- David Caplan, MD, PhD
- Neurology
Statistically significant, but imperfect, correlations exist among symptoms and signs of these neurodegenerative diseases.- Reviewing:
- Josephs KA et al., Brain 2006 Jun; 129:1385-98.
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Localizing the Muse
- March 18, 2008
- Michael Henry Rosenbloom, MD, and Bruce Price, MD
- Neurology
Data from a patient with nonfluent progressive aphasia provide insights into the creative process.- Reviewing:
- Seeley WW et al., Brain 2008 Jan; 131:39.
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Primary Progressive Aphasia - An Update
- December 31, 2003
- Elliott D. Ross, MD
- Neurology
Mesulam first described primary progressive aphasia (PPA) in 1982. He now provides a comprehensive review of the clinical, pathophysiologic, and neuropathologic aspects of PPA. PPA . . .- Reviewing:
- Mesulam M-M., N Engl J Med 2003 Oct 16; 349:1535-42.
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Intensity Matters in Post-Stroke Aphasia Therapy
- June 6, 2003
- Howard S. Kirshner, MD
- Neurology
In this analysis of published studies of speech and language therapy for aphasia after stroke, the authors primarily investigated the effect of intensity of therapy. . . .- Reviewing:
- Bhogal SK et al., Stroke 2003 Apr; 34:987-93.
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Primary Progressive Aphasia Suggests a Pick Complex Disorder
- March 27, 2003
- Michael D. Greicius, MD
- Neurology
Kertesz and Munoz hypothesized that (1) primary progressive aphasia (PPA), carefully defined, is a harbinger of Pick complex and (2) Pick complex is a valuable . . .- Reviewing:
- Kertesz A and Munoz DG., J Neurol Sci 2003 Jan 15; 206:97-107.
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Primary Progressive Aphasia: A Review
- August 23, 2001
- H Goodglass
- Neurology
In this comprehensive review of the primary progressive aphasia (PPA) syndrome, the author addresses the range of clinical presentations, their distinction from other dementing illnesses . . .- Reviewing:
- Mesulam MM., Ann Neurol 2001 Apr; 49:
425 432 .
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RH Activation Correlates with Comprehension Improvement in Aphasia
- January 1, 2000
- M Kinsbourne
- Neurology
Aphasia due to acute left hemisphere (LH) infarction spontaneously recovers to some extent. Does unaffected LH language territory compensate, or do homologous, nonverbal, right hemisphere . . .- Reviewing:
- Musso M et al., Brain 1999 Sep; 122:
1781 1790 .
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An Imaging Study of Recovery from Aphasia
- July 1, 1999
- KM Heilman
- Neurology
After hemispheric injury, recovery of behavioral function depends on whether (1) the injury caused physiological disruption or cell death, (2) areas remote from the injury . . .- Reviewing:
- Heiss et al., Ann Neurol 1999 Apr; 45:
430 438 .
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Rates of Decline and Survival in FTLD and Its Subtypes
- November 3, 2005
- David Knopman, MD
- Neurology
Survival is worse with FTLD than with AD, even among patients with comparable baseline cognitive status.- Reviewing:
- Rascovsky K et al., Neurology 2005 Aug 9; 65:397-403.
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Nonparkinsonian Diseases Caused by LRRK2 Mutations
- June 17, 2008
- D.A. Grimes, MD, FRCPC
- Neurology
Screening for LRRK2 mutations in patients with neurodegenerative diseases identified two individuals with nonparkinsonian diseases who had mutations.- Reviewing:
- Chen-Plotkin AS et al., Neurology 2008 Feb 12; 70:521.
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MRI Measures of Brain Atrophy in Frontotemporal Lobar Degeneration
- August 11, 2009
- Keith A. Johnson, MD
- Neurology
Can MRI measures of whole-brain atrophy provide useful markers for clinical treatment trials?- Reviewing:
- Knopman DS et al., Neurology 2009 May 26; 72:1843.
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Major Genetic Subtypes of Frontotemporal Dementia
- February 3, 2009
- Bruce L. Miller, MD
- Neurology
Analysis of a large cohort reveals presence of two known mutations in 17% and autosomal dominant inheritance without known mutations in another 10%.- Reviewing:
- Seelaar H et al., Neurology 2008 Oct 14; 71:1220. Grossman M., Neurology 2008 Oct 14; 71:1216.
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Cortical Demyelination in MS and Progressive Multifocal Leukoencephalopathy
- June 3, 2008
- Kenneth L. Tyler, MD
- Neurology
This study provides important information about demyelination pattern differences between these two diseases.- Reviewing:
- Moll NM et al., Neurology 2008 Jan 29; 70:336. Lassmann H and Lucchinetti CF., Neurology 2008 Jan 29; 70:332.
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Cognitive Disorders in Acute Stroke
- December 4, 2007
- Amytis Towfighi, MD
- Neurology
Cognitive deficits soon after stroke are most often associated with hemorrhagic, cortical, and left-hemispheric strokes.- Reviewing:
- Nys GM et al., Cerebrovasc Dis 2007; 23:408.
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Anosognosia: Definitions, Diagnosis, and Prognosis
- February 20, 2007
- Kenneth M. Heilman, MD
- Neurology
Much remains to be learned about this post-stroke condition.- Reviewing:
- Jehkonen M et al., Acta Neurol Scand 2006 Nov; 114:293-306.
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Features of Steroid-Responsive Encephalopathy with Thyroid Autoantibodies
- April 6, 2006
- Inga Zerr, MD
- Neurology
In the absence of a definitive test, a high degree of suspicion for this condition is warranted in patients with rapidly progressing dementia.- Reviewing:
- Castillo P et al., Arch Neurol 2006 Feb; 63:197-202.
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MRI Aids Assessment of Stroke Risk After Minor Stroke or TIA
- October 6, 2005
- Harold P. Adams, Jr., MD
- Neurology
The high risk associated with findings on MRI supports urgent assessment of these patients.- Reviewing:
- Coutts SB et al., Ann Neurol 2005 Jun; 57:848-54.
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Examination of Multiple Language Functions in Temporal Lobe Epilepsy
- June 23, 2005
- Howard S. Kirshner, MD
- Neurology
These authors studied language functions in 23 patients with medically refractory temporal lobe epilepsy (TLE) defined by a unilateral seizure-onset zone according to ictal EEG, . . .- Reviewing:
- Bartha L et al., J Neurol Neurosurg Psychiatry 2005 Jun; 76:808-14.
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Which Brain Regions Mediate Stability of Cognitive and Behavioral Performance?
- April 9, 2004
- Kirk R. Daffner, MD
- Neurology
In this study, researchers investigated whether damage to specific brain regions is associated with increased variability of task performance. They used four reaction-time (RT) tasks . . .- Reviewing:
- Stuss DT et al., Brain 2003 Nov; 126:2363-80.
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