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Search for Multiple Sclerosis in Neurology
Physician-authored summaries on the latest research on multiple sclerosis, editorials on multiple sclerosis, and perspectives on multiple sclerosis - drawn from the top medical journals.
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You searched for: multiple sclerosis in Neurology
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Exclusive Breast-Feeding and Risk for Postpartum MS Relapse
- August 4, 2009
- Patricia K. Coyle, MD
- Neurology
In a small study, exclusive breast-feeding was associated with reduced postpartum relapses.- Reviewing:
- Langer-Gould A et al., Arch Neurol 2009 Jun 8;:
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Brain Iron Deposition in Multiple Sclerosis
- April 28, 2009
- Rohit Bakshi, MD, FAAN
- Neurology
Using a novel MRI technique, investigators provide additional evidence of excessive iron deposition in cerebral gray and white matter in patients with MS.- Reviewing:
- Hammond KE et al., Ann Neurol 2008 Dec; 64:707.
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Effectiveness of Rehabilitation in Multiple Sclerosis
- April 7, 2009
- John F. Kurtzke, MD, FACP, FAAN
- Neurology
Can newer treatment-trial methods show that comprehensive rehabilitation is effective?- Reviewing:
- Khan F et al., J Neurol Neurosurg Psychiatry 2008 Nov; 79:1230.
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Statin Use in Multiple Sclerosis
- February 24, 2009
- Robert J. Fox, MD
- Neurology
A small study suggests increased MS activity with atorvastatin added to interferon-β, but the implications are unclear.- Reviewing:
- Birnbaum G et al., Neurology 2008 Oct 28; 71:1390. Goldman MD and Cohen JA., Neurology 2008 Oct 28; 71:1386.
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Is Benign Multiple Sclerosis Truly Benign? Free
- February 3, 2009
- Maria K. Houtchens, MD, MMSci
- Neurology
A diffusion tensor MRI study suggests not.- Reviewing:
- Rovaris M et al., Neurology 2008 Nov 4; 71:1521.
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Reduced CSF Endocannabinoid Levels in MS
- January 27, 2009
- Leslie L. Iversen, PhD
- Neurology
Patients had lower levels than healthy controls did, supporting a role of these compounds in neuroinflammation.- Reviewing:
- Di Filippo M et al., J Neurol Neurosurg Psychiatry 2008 Nov; 79:1224.
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Abnormal Sympathetic Skin Responses in MS
- December 30, 2008
- Christopher H. Hawkes, MD, FRCP
- Neurology
Do abnormalities correlate with lesion load?- Reviewing:
- Saari A et al., Acta Neurol Scand 2008 Oct; 118:226.
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Evidence-Based Review of Natalizumab in MS
- November 25, 2008
- Aaron E. Miller, MD
- Neurology
A review of the benefits and risks from this treatment- Reviewing:
- Goodin DS et al., Neurology 2008 Sep 2; 71:766.
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IVIG for Relapsing-Remitting Multiple Sclerosis
- November 18, 2008
- Benjamin M. Greenberg, MD, MHS
- Neurology
A dose-finding trial unexpectedly produces negative results.- Reviewing:
- Fazekas F et al., Neurology 2008 Jul 22; 71:265.
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Mitochondria and Multiple Sclerosis
- September 30, 2008
- Michio Hirano, MD
- Neurology
Do mitochondrial defects contribute to acute lesions in multiple sclerosis?- Reviewing:
- Mahad D et al., Brain 2008 Jul; 131:1722.
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Changes in MS Incidence During a Half-Century
- September 9, 2008
- Milton Alter, MD, PhD
- Neurology
The historical latitude gradient in MS incidence appears to have diminished more recently, while the female-to-male ratio has increased.- Reviewing:
- Alonso A and Hernán MA., Neurology 2008 Jul 8; 71:129.
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Symptoms Without Signs Predict No MS
- September 2, 2008
- Jacqueline Palace, BM, DM, FRCP
- Neurology
Symptoms without objective evidence did not lead to MS in a study with a median of 4.4 years of follow-up.- Reviewing:
- Boster A et al., Mult Scler 2008 Jul; 14:804.
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Genetic Prediction of Interferon β Efficacy in Multiple Sclerosis
- July 8, 2008
- Orhun H. Kantarci, MD
- Neurology
A genome-wide screening study identifies candidates that may one day be used to identify patients likely to respond to the drug.- Reviewing:
- Byun E et al., Arch Neurol 2008 Mar; 65:337.
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Oligoclonal Bands and MRI in First Attack of Multiple Sclerosis
- June 17, 2008
- Clive Hawkins, MD, DM
- Neurology
Independent of MRI findings, the presence of oligoclonal bands predicts conversion to clinically definite MS.- Reviewing:
- Tintoré M et al., Neurology 2008 Mar 25; 70:1079. Hintzen RQ and Giovannoni G., Neurology 2008 Mar 25; 70:1059.
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Does the Vitamin D Emperor Have Clothes? Free
- May 27, 2008
- John F. Kurtzke, MD, FACP, FAAN
- Neurology
Vitamin D levels may not correlate with disease activity in MS, despite statistically significant findings in this study.- Reviewing:
- Soilu-Hänninen M et al., J Neurol Neurosurg Psychiatry 2008 Feb; 79:152.
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Seeing is Believing
- March 25, 2008
- Marc Dinkin, MD
- Neurology
A new study links loss of low-contrast visual acuity to global and occipital lobe T2-lesion burden in MS.- Reviewing:
- Wu GF et al., Neurology 2007 Dec 4; 69:2128. Frohman EM and Zivadinov R., Neurology 2007 Dec 4; 69:2119.
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B-Cell Depletion for MS Free
- February 13, 2008
- Samia J. Khoury, MD
- Neurology
Rituximab showed promising results in a preliminary trial.- Reviewing:
- Hauser SL et al., N Engl J Med 2008 Feb 14; 358:676.
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Thalamic Atrophy Predicts Cognitive Changes in MS
- January 29, 2008
- Istvan Pirko, MD
- Neurology
In regression models predicting cognitive changes in MS, thalamic atrophy entered and remained in the models more frequently than did other volumetric MRI measurements.- Reviewing:
- Houtchens MK et al., Neurology 2007 Sep 18; 69:1213.
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Aquaporin-4 Autoantibodies in Japanese MS Patients
- December 18, 2007
- Brian G. Weinshenker, MD, FRCP(C)
- Neurology
These autoantibodies are associated with long spinal-cord lesions and severe visual impairment in Japanese patients with MS.- Reviewing:
- Tanaka M et al., J Neurol Neurosurg Psychiatry 2007 Sep; 78:990.
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Link Between IL7R Polymorphisms and MS Reaffirmed
- November 6, 2007
- Samia J. Khoury, MD
- Neurology
Although one single nucleotide polymorphism generally is associated with slightly increased multiple sclerosis risk, IL7R’s most common haplotype confers protection.- Reviewing:
- Gregory SG et al., Nat Genet 2007 Sep; 39:1083. Lundmark F et al., Nat Genet 2007 Sep; 39:1108.
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