Tai Chi vs. Other Exercises for Parkinson Disease
SUMMARY AND COMMENT
A randomized comparison suggests potential benefits from both tai chi and resistance training.
Reviewing:
Li F et al., N Engl J Med 2012 Feb 9; 366:511
Best Treatment for Acute and Subacute Neck Pain?
SUMMARY AND COMMENT
February 7, 2012
Jaime Toro, MD
In a randomized trial, spinal manipulation and home exercise seemed superior to medication for this common condition, but patient preference should be considered.
Reviewing:
Bronfort G et al., Ann Intern Med 2012 Jan 3; 156:1
Walker BF., Ann Intern Med 2012 Jan 3; 156:52
Nicotine for MCI?
SUMMARY AND COMMENT
February 7, 2012
David S. Knopman, MD
A small study of a nicotine patch in patients with mild cognitive impairment showed some benefit on a reaction-time test but no effect according to clinicians' judgment.
Reviewing:
Newhouse P et al., Neurology 2012 Jan 10; 78:91
Statin Use and Hemorrhage After Ischemic Stroke
SUMMARY AND COMMENT
February 7, 2012
Seemant Chaturvedi, MD
No increase in risk for hemorrhagic stroke was seen with statin use after intracerebral hemorrhage in a database study.
Reviewing:
Hackam DG et al., Arch Neurol 2012 Jan; 69:39
Stroke Hospitalizations Among the Young
SUMMARY AND COMMENT
February 7, 2012
Christine Fox, MD
The prevalence of ischemic stroke hospitalizations among people younger than 45 may have risen in recent years.
Reviewing:
George MG et al., Ann Neurol 2011 Nov; 70:713
Stroke Survivors Face a High Burden of Vascular Dementia
SUMMARY AND COMMENT
February 7, 2012
Hooman Kamel, MD
Delayed dementia after stroke is common and appears to reflect mostly vascular pathology.
Reviewing:
Allan LM et al., Brain 2011 Dec; 134:3716
Neuromyelitis Optica Treatment with Targeted Molecular Therapy
SUMMARY AND COMMENT
A proof-of-concept study establishes the effectiveness of therapy with a monoclonal antibody specific to aquaporin-4 in animal models.
Reviewing:
Tradtrantip L et al., Ann Neurol 2012 Jan 23
Improvement in Visual Function with Stem-Cell Therapy in Progressive MS
SUMMARY AND COMMENT
A small, open-label, proof-of-concept study suggests clinical and electrophysiological benefits.
Reviewing:
Connick P et al., Lancet Neurol 2012 Feb; 11:150
Firategrast Demonstrates Efficacy in Relapsing MS
SUMMARY AND COMMENT
A phase II trial demonstrated reduction in enhancing magnetic resonance imaging lesions in patients with multiple sclerosis.
Reviewing:
Miller DH et al., Lancet Neurol 2012 Feb; 11:131
Addressing Abuse of Neurology Patients
SUMMARY AND COMMENT
A position statement from the American Academy of Neurology
Reviewing:
Schulman EA and Hohler AD., Neurology 2012 Feb 7; 78:433