ADAGIO/Rasagiline Study: Has Neuroprotection Been Achieved?
SUMMARY AND COMMENT
November 17, 2009
Lewis Sudarsky, MD
The study, along with previous research, supports a beneficial effect of MAO-B inhibitors on progression of motor disability, if not on the neurobiology of Parkinson disease.
Reviewing:
Olanow CW et al., N Engl J Med 2009 Sep 24; 361:1268
Neuromyelitis Serostatus in Fulminant CNS Demyelinating Disease
SUMMARY AND COMMENT
November 17, 2009
Charles M. Poser, MD, FRCP
What does NMO-IgG presence in serum indicate?
Reviewing:
Magaña SM et al., Arch Neurol 2009 Aug; 66:964
A Confused Patient
CASE HISTORY
A case description and diagnosis and an expert's discussion
In Search of the Cortical Signature of Early Alzheimer Disease
SUMMARY AND COMMENT
November 10, 2009
Liana Apostolova, MD
A new technique shows promise for identifying patients in the early stages of AD.
Reviewing:
Bakkour A et al., Neurology 2009 Mar 24; 72:1048
Meta-Analysis of Treatments for Bell Palsy
SUMMARY AND COMMENT
November 10, 2009
Don Gilden, MD
An update on the evidence for using corticosteroids, antivirals, or both
Reviewing:
de Almeida JR et al., JAMA 2009 Sep 2; 302:985
Preventative Treatment of Intracranial Aneurysms
SUMMARY AND COMMENT
November 3, 2009
Rose Du, MD, PhD
A new cost-effectiveness analysis addresses some clinically important questions.
Reviewing:
Greving JP et al., Neurology 2009 Jul 28; 73:258
Torner JC et al., Neurology 2009 Jul 28; 73:254
Genetic Causes of Dopa-Responsive Dystonia
SUMMARY AND COMMENT
November 3, 2009
Nutan Sharma, MD, PhD
Parkinsonism is not the only clinical syndrome associated with abnormal dopamine levels.
Reviewing:
Clot F et al., Brain 2009 Jul; 132:1753
Quality of Life with Psychogenic Nonepileptic Seizures
SUMMARY AND COMMENT
November 3, 2009
Gregory Fricchione, MD
Psychiatric symptoms affect quality of life more than seizure frequency does.
Reviewing:
LaFrance WC Jr and Syc S., Neurology 2009 Aug 4; 73:366
Subjectively Poor Sleep Correlates with Postpartum Depression
SUMMARY AND COMMENT
November 3, 2009
Brian J. Murray MD, FRCPC D, ABSM
In a questionnaire study, this association held true even after adjustments for other known risk factors for depression.
Reviewing:
Dørheim SK et al., Sleep 2009 Jul; 32:847
Psychological Health in Central Hypersomnias: The French Harmony Study
SUMMARY AND COMMENT
October 27, 2009
Demetrios A. Julius, MD
An ambitious and impressive study of central hypersomnias — including cataplectic narcolepsy, narcolepsy without cataplexy, and idiopathic hypersomnia — helps to clarify the associations of these entities with each other, with depressive symptomatology, and with treatment response.
Reviewing:
Dauvilliers Y et al., J Neurol Neurosurg Psychiatry 2009 Jun; 80:636