Neurology: Archives

SUMMARY AND COMMENT

The Enigma of Evening and Weekend Stroke

• August 25, 2009
• Steven R. Levine, MD

In a large database study, mortality was slightly higher with off-hours stroke admissions than with normal-hours admissions, despite similar treatment according to quality-of-care measures.

• Reviewing:
• Reeves MJ et al., Stroke 2009 Feb; 40:569

SUMMARY AND COMMENT

Update on Restless Legs Syndrome and Vascular Disease

• August 25, 2009
• Kapil Sethi, MD

A review of the evidence highlights an association, but causality remains uncertain.

• Reviewing:
• Walters AS and Rye DB., Sleep 2009 May 1; 32:589

SUMMARY AND COMMENT

Fatal Deer Tick Virus Encephalitis in New York State

• August 18, 2009
• Christina M. Marra, MD

A report of a patient with encephalitis caused by deer tick virus, a form of Powassan virus not previously known to cause encephalitis in humans

• Reviewing:
• Tavakoli NP et al., N Engl J Med 2009 May 14; 360:2099

SUMMARY AND COMMENT

Botulinum Toxin for Diabetic Neuropathic Pain

• August 18, 2009
• Daniel D. Truong, MD

Promising results from a small study

• Reviewing:
• Yuan R-Y et al., Neurology 2009 Apr 28; 72:1473

SUMMARY AND COMMENT

MRI Measures of Brain Atrophy in Frontotemporal Lobar Degeneration

• August 11, 2009
• Keith A. Johnson, MD

Can MRI measures of whole-brain atrophy provide useful markers for clinical treatment trials?

• Reviewing:
• Knopman DS et al., Neurology 2009 May 26; 72:1843

SUMMARY AND COMMENT

Effect of Clopidogrel Added to Aspirin in Patients with Atrial Fibrillation

• August 11, 2009
• J. Philip Kistler, MD

In patients who were "unsuitable" for warfarin, clopidogrel plus aspirin prevented more ischemic strokes than aspirin alone.

• Reviewing:
• Connolly SJ et al. for the ACTIVE Investigators., N Engl J Med 2009 May 14; 360:2066 Go AS., N Engl J Med 2009 May 14; 360:2127

SUMMARY AND COMMENT

Alzheimer Disease and Inflammation: More Epidemiology, More Questions

• August 4, 2009
• Joseph Rogers, PhD

For anti-inflammatory approaches to Alzheimer disease, timing may be everything.

• Reviewing:
• Breitner JCS et al., Neurology 2009 Jun 2; 72:1899 Bennett DA and Whitmer RA., Neurology 2009 Jun 2; 72:1884

SUMMARY AND COMMENT

Transcranial Doppler Ultrasound for Primary Stroke Prevention in Sickle Cell Disease

• August 4, 2009
• Farzaneh A. Sorond, MD, PhD

An analysis of change in rates of use and barriers to screening

• Reviewing:
• Armstrong-Wells J et al., Neurology 2009 Apr 14; 72:1316

SUMMARY AND COMMENT

Effects of Diabetes and Adiposity on Cognition in Elders

• August 4, 2009
• Joseph I. Friedman, MD

Two studies suggest differential patterns of cognitive decline or dementia, one between men and women with increased adiposity, the other between patients with and without diabetes.

• Reviewing:
• Kanaya AM et al., Arch Neurol 2009 Mar; 66:329 Sonnen JA et al., Arch Neurol 2009 Mar; 66:315

SUMMARY AND COMMENT

Exclusive Breast-Feeding and Risk for Postpartum MS Relapse

• August 4, 2009
• Patricia K. Coyle, MD

In a small study, exclusive breast-feeding was associated with reduced postpartum relapses.

• Reviewing:
• Langer-Gould A et al., Arch Neurol 2009 Jun 8