Neurology: Archives

SUMMARY AND COMMENT

Cognitive Effects of Antiepileptic Drug Withdrawal

• June 2, 2009
• Kimford J. Meador, MD

Withdrawal in patients with well-controlled seizures produced significant improvements on cognitive-test performance.

• Reviewing:
• Hessen E et al., Acta Neurol Scand 2009 Mar; 119:194

SUMMARY AND COMMENT

A Novel Target for Glioblastoma TherapyFree

• June 2, 2009
• Santosh Kesari, MD, PhD

A genomewide mutational analysis might pave the way to personalizing brain tumor treatments based on molecular subtypes.

• Reviewing:
• Yan H et al., N Engl J Med 2009 Feb 19; 360:765

SUMMARY AND COMMENT

Prompt TIA and Minor Stroke ManagementFree

• May 26, 2009
• Hermelinda Abcede, MD, and Bruce Ovbiagele, MD

Urgent referral to and treatment in a specialized clinic boosts clinical outcomes and saves costs.

• Reviewing:
• Luengo-Fernandez R et al., Lancet Neurol 2009 Mar; 8:235

SUMMARY AND COMMENT

Stenting in Acute Ischemic Stroke

• May 26, 2009
• Thanh Nguyen, MD, FRCPc

A small study suggests stenting might be useful as an adjunctive therapy.

• Reviewing:
• Brekenfeld C et al., Stroke 2009 Mar; 40:847

SUMMARY AND COMMENT

Antivenom for Scorpion Stings

• May 26, 2009
• Michael R. Dobbs, MD

Children with severe reactions to stings recovered quickly after receiving antivenom.

• Reviewing:
• Boyer LV et al., N Engl J Med 2009 May 14; 360:2090

SUMMARY AND COMMENT

Research Criteria for Behavioral-Variant Frontotemporal Dementia

• May 19, 2009
• William W. Seeley, MD

Is it time to revise the criteria from 1998?

• Reviewing:
• Piguet O et al., Neurology 2009 Feb 24; 72:732

CLINICAL PRACTICE GUIDELINE WATCH

Guideline Watch: USPSTF Guidelines on Folic Acid Supplementation

• May 19, 2009
• The Editors

Updated recommendations on supplementation to prevent neural tube defects

• Reviewing:
• U.S. Preventive Services Task Force., Ann Intern Med 2009 May 5; 150:626 Wolff T et al., Ann Intern Med 2009 May 5; 150:632

SUMMARY AND COMMENT

Long-Term Outcome in Fetal Cell Transplants for Parkinson Disease

• May 5, 2009
• Lewis Sudarsky, MD

Transplanted cells develop pathology identical to the Lewy bodies seen in PD.

• Reviewing:
• Kordower JH et al., Mov Disord 2008 Dec 15; 23:2303

SUMMARY AND COMMENT

Brain Iron Deposition in Multiple Sclerosis

• April 28, 2009
• Rohit Bakshi, MD, FAAN

Using a novel MRI technique, investigators provide additional evidence of excessive iron deposition in cerebral gray and white matter in patients with MS.

• Reviewing:
• Hammond KE et al., Ann Neurol 2008 Dec; 64:707

SUMMARY AND COMMENT

Long-Term Antipsychotic Use in Alzheimer Disease

• April 28, 2009
• Zeina Chemali, MD, MPH

Mortality was higher with 1 year of antipsychotic use than with placebo and appeared to increase with longer-term follow-up.

• Reviewing:
• Ballard C et al., Lancet Neurol 2009 Feb; 8:151